Understanding the Role of Genetic Testing in
Chronic Myeloid Leukaemia [CML]
The aim of treatment is
to bring down the
BCR-ABL1 level, which
is the diagnostic
indicator for CML
The red line on this
diagram shows role of
genetic testing to monitor
response to treatment. In
the first instance with a
first generation drug and
then appropriate choice
of 2nd generation drug if
suboptimal or loss of
response.
Ongoing lifetime
monitoring to check for
relapse.
These are high cost
therapies and genetic
testing helps to select the
one with the best likely
clinical outcome
